Gill EROD Activity in Fish A Biomarker for Waterborne Ah-receptor Agonists
نویسنده
چکیده
List of papers This thesis is based on the following papers, which will be referred to in the text by their Roman numerals.rigtsen K, Jørgensen EH. 2003. EROD activity in gills of anadromous and marine fish as a biomarker of dioxin-like pollutants.rome P4501A induction in rainbow trout gills and liver following exposure to waterborne indigo, benzo(a)pyrene and 3,3',4,4',5-pentachlorobiphenyl. in monitoring of CYP1A inducers in fish – a study in rainbow trout (Oncor-hynchus mykiss) caged in urban waters in Sweden. Manuscript V Abrahamson A, Brunström B, Brandt I. Inhibition of CYP1A activity in fish detected by the gill filament EROD assay – studies on ketoconazole, bitertanol, acacetin and omeprazole. Manuscript Reprints of Papers I and II were made with permission of the publisher.
منابع مشابه
Azoles and Contaminants in Treated Effluents Interact with CYP1 and CYP19 in Fish
Beijer, K. 2015. Azoles and Contaminants in Treated Effluents Interact with CYP1 and CYP19 in Fish. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1255. 42 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9248-9. Numerous contaminants are present in mixtures in the aquatic environment. Among these are the azoles, a group of chemic...
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The effect of cytochrome P4501A (CYP1A) induction on cell-specific benzo[a]pyrene (BaP) adduct formation was studied in rainbow trout (Oncorhynchus mykiss) gills. Fish preexposed to beta-naphthoflavone (betaNF) or caged in a polluted river were exposed to waterborne 3H-benzo[a]pyrene (3H-BaP). The 3H-benzo[a]pyrene adducts in the gill filaments were localized by autoradiography and CYP1A protei...
متن کاملEffects of Beta-Naphthoflavone and 3-Methylcholantheren on Biochemical Markers in Sturgeon Fish, Huso huso
Background: Polycyclic aromatic hydrocarbons (PAHs) are a predominant group of contaminants that have been shown to accumulate and persist in marine organisms. We evaluated the dose-dependent induction of the cytochrome P4501A (CYP1A) system in the Sturgeon fish, Huso huso after after exposure to PAHs, beta-naphthoflavone (BNF) and 3- methylcholantheren. Methods: The fish were treated by i.p...
متن کاملEvaluation of Biomarker Responses in Fish with Special Emphasis on Gill EROD Activity
List of papers The present thesis is based on the following papers, which will be referred to by their Roman numerals.
متن کاملErod Activity
Measurement of ethoxyresorufin-O-deethylase (EROD) activity in fish is a well-established in vivo biomarker of exposure to certain planar halogenated and polycyclic aromatic hydrocarbons (PHHs and PAHs) and other structurally similar compounds (Bucheli and Fent 1995; Stegeman and Hahn 1994). EROD is a highly sensitive indicator of contaminant uptake in fish, providing evidence of receptor-media...
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